is metformin a glp-1 receptor agonist Better outcomes with GLP-1s in those with diabetes and peripheral arterial disease Metformin decreases liver production of

This drug may cause side effects, including nausea/vomiting, diarrhea, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, hypersensitivity reactions, gas, hair loss, GERD, abdominal distension, dizziness, and low blood pressure

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Weight loss Available in NZ = Liraglutide high dose (Saxenda, daily injection) Self-funding needed ($500-600/month) Not available in NZ = Semaglutide (Ozempic, Wegovy) or Tirzepatide (Mounjaro), as of May 2023 Side effects, particularly upper gastrointestinal, are common with GLP-1 agonist initiation

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HYDROTHERAPY is another technique you might consider

The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles